A room temperature decarboxylation/C-H functionalization cascade by visible-light photoredox catalysis.
نویسندگان
چکیده
An elegant approach to quaternary oxindole formation has been developed through a room temperature decarboxylation/radical C-H functionalization by visible-light photoredox catalysis.
منابع مشابه
C-H functionalization of phenols using combined ruthenium and photoredox catalysis: in situ generation of the oxidant.
A combination of ruthenium and photoredox catalysis allowed the ortho olefination of phenols. Using visible light, the direct C-H functionalization of o-(2-pyridyl)phenols occurred, and diverse phenol ethers were obtained in good yields. The regeneration of the ruthenium catalyst was accomplished by a photoredox-catalyzed oxidative process.
متن کاملMerging Visible Light Photoredox Catalysis with Metal Catalyzed C–H Activations: On the Role of Oxygen and Superoxide Ions as Oxidants
The development of efficient catalytic systems for direct aromatic C-H bond functionalization is a long-desired goal of chemists, because these protocols provide environmental friendly and waste-reducing alternatives to classical methodologies for C-C and C-heteroatom bond formation. A key challenge for these transformations is the reoxidation of the in situ generated metal hydride or low-valen...
متن کاملMerging visible-light photoredox and Lewis acid catalysis for the functionalization and arylation of glycine derivatives and peptides.
A relay catalysis protocol for the functionalization of α-amino acids and dipeptides using a combination of visible-light photoredox and Lewis acid catalysis has been developed.
متن کاملCascade photoredox/gold catalysis: access to multisubstituted indoles via aminoarylation of alkynes.
A new method for the synthesis of 3-arylindoles has been developed by visible light mediated dual gold/photoredox catalysis. This transformation has many features such as cascade catalysis, high efficiency, redox-neutral reaction conditions and good functional group tolerance. The reaction proceeds through the photoredox-promoted formation of an electrophilic arylgold(iii) intermediate that und...
متن کاملTransition-metal-free visible-light photoredox catalysis at room-temperature for decarboxylative fluorination of aliphatic carboxylic acids by organic dyes.
We report herein an efficient, general and green method for decarboxylative fluorination of aliphatic carboxylic acids. By using a transition-metal-free, organocatalytic photoredox system, the reaction of various aliphatic carboxylic acids with the Selectfluor reagent afforded the corresponding alkyl fluorides in satisfactory yields under visible light irradiation at room temperature.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 49 50 شماره
صفحات -
تاریخ انتشار 2013